Cancer Biology
Doug Frantz, PhD
Professor
- Email: dougf@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Cancer Biology
Neurosciences
Immunology
Developmental Regenerative and Stem Cell Biology
Research summary
Small molecule drug discovery inspired research across multiple therapeutic areas including chronic pain, oncology, and neurodegeneration.
Key words
drug discovery, medicinal chemistry, chemical biology, synthetic methods
Aimilia Gastounioti, PhD
Assistant Professor
- Email: a.gastounioti@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Cancer Biology
Research summary
Translational research in the intersection of computational breast imaging, artificial intelligence, and informatics towards improving breast cancer screening
Key words
breast cancer, computational imaging analytics, machine learning, deep learning, artificial intelligence, big data, data science, precision medicine
Aliereza Ghanbarpour, PhD
Assistant Professor
- Email: alirezag@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Cancer Biology
Computational and Systems Biology
Research summary
Our research focuses on unraveling the molecular mechanisms underlying substrate specificity and degradation by AAA proteolytic machines and their associated adaptor proteins, utilizing structural biology, biochemistry, and cellular assays in both bacteria and human mitochondria.
Key words
AAA proteases, cryo-EM, biochemistry, mass spectrometry, structural biology, microbiology, mitochondria
William Gillanders, MD
Professor
- Email: gillandersw@wustl.edu
Program affiliation
Immunology
Cancer Biology
Research summary
Development of a breast cancer vaccine
Key words
antigen presentation, breast cancer, translational research, T cells, vaccine
Felicia Gomez, PhD
Assistant Professor
- Email: fgomez@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Molecular Genetics and Genomics
Cancer Biology
Research summary
Key words
Matthew Goodwin, MD, PhD
Assistant Professor
- Email: matthewlgoodwin@wustl.edu
Program affiliation
Molecular Cell Biology
Cancer Biology
Molecular Genetics and Genomics
Research summary
Metabolism of cancer, targeting tumor metabolism by blocking metabolic pathways
Key words
Abby Green, MD
Associate Professor
- Email: abby.green@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
The etiology of mutagenesis and genome instability in pediatric cancers
Key words
leukemia, pediatric cancer, DNA damage, DNA replication, hematopoiesis
Eric Greer, PhD
Associate Professor
- Email: ericg@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
Deciphering the molecular mechanisms of epigenetics and how when this goes awry diseases arise
Key words
Epigenetics, Transgenerational, Imprinting, Evolution, Multicellularity, Cancer, Tumorigenesis, Epitranscriptomics
Malachi Griffith, PhD
Associate Professor
- Email: mgriffit@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Cancer Biology
Computational and Systems Biology
Research summary
Improving our understanding of human disease biology and the development of personalized medicine strategies using genomics and informatics technologies
Key words
genomics, bioinformatics, data mining, immunogenomics, precision medicine, personalized medicine, cancer vaccines, and cancer research
Obi Griffith, PhD
Professor
- Email: obigriffith@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Cancer Biology
Molecular Cell Biology
Immunology
Research summary
Development of personalized medicine strategies for cancer using genomic technologies
Key words
bioinformatics, machine learning, cancer, genomics, immunogenomics, precision oncology