Computational and Systems Biology
Albert Kim, MD, PhD
August A. Busch, Jr. Professor
- Email: alberthkim@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Computational and Systems Biology
Neurosciences
Cancer Biology
Research summary
Genetic and epigenetic changes that drive malignant behavior in brain tumors
Key words
brain tumors, glioblastoma, meningioma, neural stem cells
Eynav Klechevsky, PhD
Assistant Professor
- Email: eklechevsky@wustl.edu
Program affiliation
Immunology
Cancer Biology
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Research summary
understand the biology of different human dendritic cells and other myeloid cells as a key for manipulating immune responses in various disease conditions
Key words
Human Immunology, Dendritic Cells, Tumor Immunology, immune dysfunctions, Vaccines
Dmitri Kotov, PhD
Assistant Professor
- Email: kotov@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Research summary
My lab works on the host immune response to Mycobacterium tuberculosis. We use mouse models that mimic key aspects of human disease to gain a mechanistic understanding of the host response allowing for the identification of novel targets for host-directed therapies.
Key words
Mycobacterium tuberculosis, innate immunology, macrophages, neutrophils, dendritic cells
Shinjini Kundu, PhD, MD
Assistant Professor
- Email: kundu@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Neurosciences
Computational and Systems Biology
Research summary
Key words
Sebla Kutluay, PhD
Associate Professor
- Email: kutluay@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Research summary
Human immunodeficiency virus-host interactions
Key words
Albert Lai, PhD
Associate Professor
- Email: amlai@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Research summary
My research is in clinical research informatics, but I also have strong interest in other areas of clinical informatics, including usability of clinical and consumer-facing systems and mobile health
Key words
Brian Laidlaw, PhD
Assistant Professor
- Email: brian.laidlaw@wustl.edu
Program affiliation
Immunology
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Investigating the development of immunological memory in disease states
Key words
B cells, immunological memory, germinal center, virus, allergy
Michael Landis, PhD
Assistant Professor
- Email: michael.landis@wustl.edu
Program affiliation
Ecology and Evolutionary Biology
Computational and Systems Biology
Molecular Genetics and Genomics
Research summary
Modeling the evolution of species with stochastic processes [Recruiting PhD Students for Fall 2024]
Key words
phylogenetics, evolution, ecology, epidemiology, statistical models, stochastic processes, computational inference, deep learning
Timothy Laumann, MD, PhD
Assistant Professor
- Email: laumannt@wustl.edu
Program affiliation
Neurosciences
Computational and Systems Biology
Research summary
Key words
Heather Lawson, PhD
Assistant Professor
- Email: lawson@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Human and Statistical Genetics
Ecology and Evolutionary Biology
Research summary
Integration of whole-genome sequence with phenotypic data to understand parent-of-origin genetic effects and gene-by-environment interactions
Key words
Epigenetics, gene regulation, parent-of-origin effects, gene-by-environment interactions, pleiotropy, systems biology, metabolism, evolution