Developmental Regenerative and Stem Cell Biology
Jeffrey Millman, PhD
Professor
- Email: jmillman@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
Differentiation to and maturation of pancreatic insulin-producing β cells from human pluripotent stem cells capable of rapidly reversing diabetes
Key words
stem cell biology, regeneration, developmental biology, microscopy, single-cell RNA-sequencing, differentiation, tissue engineering, diabetes, organoids, transplantation, therapy
Mayssa Mokalled, PhD
Associate Professor
- Email: mmokalled@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Neurosciences
Molecular Genetics and Genomics
Research summary
Mechanisms of neural regeneration using zebrafish and mouse model systems
Key words
Josh Morgan, PhD
Assistant Professor
- Email: jlmorgan@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Ecology and Evolutionary Biology
Research summary
Use advanced cellular imaging techniques to investigate how neurons organize themselves into image processing circuits
Key words
connectomics, vision, retina, LGN, synapse, electron microscopy, circuit
Kenneth Murphy, MD, PhD
Eugene Opie First Centennial Professor
- Email: kmurphy@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
Dendritic cell development and diversification
Key words
Dendritic cell and T cell differentiation, gene expression, transcription, inflammation
David Ornitz, MD, PhD
Alumni Endowed Professor
- Email: dornitz@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Neurosciences
Research summary
Regulation of lung, skeletal, and cardiovascular development, injury response, and regeneration by Fibroblast Growth Factors
Key words
cell signaling; development; fibroblast growth factors; mouse models; stem cells, regeneration; pulmonary hypertension; alveologenesis; endocrine signaling
Miranda Orr, PhD
Associate Professor
- Email: orr.m@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Computational and Systems Biology
Immunology
Research summary
Key words
Philip Osdoby, PhD
Professor
- Email: osdoby@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
Bone remodeling cell and molecular events of osteoclast activity and development
Key words
extracellular matrix, bone biology, development, aging, osteoclast
Hysell Oviedo, PhD
Assistant Professor
- Email: hysell@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Computational and Systems Biology
Research summary
My research program aims to understand the neural circuits that underlie vocal communication processing and investigate how these circuits are disrupted in neuropsychiatric disorders.
Key words
Auditory System, Neuropsychiatric Disorders, Mouse Models, Communication Processing, Development
B. Duygu Ozpolat, PhD
Assistant Professor
- Email: bdozpolat@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Plant and Microbial Biosciences
Research summary
Mechanisms of reproductive cell regeneration and development
Key words
germline, reproduction, stem cells, regeneration, imaging, scRNAseq
Stephen Persaud, MD,PhD
Assistant Professor
- Email: persaud@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Cancer Biology
Research summary
Optimizing hematopoietic stem cell transplantation as definitive therapy for non-malignant blood diseases
Key words
sickle cell disease, hematopoietic stem cell transplantation, antibody-based immunotherapy, conditioning, JAK inhibitors, gene editing