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Regina Clemens, MD, PhD

Assistant Professor

Program affiliation
Immunology
Molecular Cell Biology

Research summary
The mechanisms regulating calcium-dependent neutrophil activation

Key words

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Marco Colonna, MD

Robert Rock Belliveau MD Professor

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Neurosciences

Research summary
Innate immune responses in infections, autoimmunity and tumors

Key words
immunology, inflammation, dendritic cells, lymphocytes, receptors, virus, gut, mucosa

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Megan Cooper, MD, PhD

Anthony R. French, MD, PhD, Professor

Program affiliation
Immunology
Human and Statistical Genetics

Research summary
The Cooper laboratory is focused on investigating the molecular and immunologic basis of inborn errors of immunity. We are particularly interested in understanding novel genetic causes of these diseases in children with immune dysregulation syndromes.

Key words
inborn errors of immunity, genetics, primary immunodeficiency STAT3, TLR8, Pediatrics

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Richard Cote, MD

Professor and Head of the Department of Pathology and Immunology

Program affiliation
Immunology
Cancer Biology

Research summary
Pathways of tumor progression and response to therapy, particularly in bladder and prostate cancer, cancer metastasis research through analysis of lymph node and bone marrow occult metastases

Key words

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David Curiel, MD, PhD

Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology
Developmental Regenerative and Stem Cell Biology

Research summary
To address the central mandate of gene therapy we engineer adenovirus tropism to allow the achievement of effective gene delivery

Key words
Adenovirus, virotherapy, virus, cancer, gene therapy, vaccine

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Mai Dang, MD, PhD

Assistant Professor

Program affiliation
Neurosciences
Cancer Biology
Immunology

Research summary

Key words

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Albert Davis, MD, PhD

Assistant Professor

Program affiliation
Neurosciences
Molecular Cell Biology
Immunology
Biochemistry Biophysics and Structural Biology

Research summary
Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies

Key words

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David DeNardo, PhD

Professor

Program affiliation
Cancer Biology
Molecular Cell Biology
Immunology

Research summary
Molecular Mechanisms of Immune Regulation of Tumor Progression.

Key words
immunotherapy, breast cancer, pancreatic cancer, immunology, inflammation, metastasis, storm

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Carl DeSelm, MD, PhD

Assistant Professor

Program affiliation
Immunology
Cancer Biology
Molecular Cell Biology

Research summary
Dr. DeSelm clinically focuses on treating lymphoma, and is actively developing novel CAR T cell approaches to treating solid tumors, including lymphoma, pancreatic cancer and glioblastoma.

Key words

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Michael Diamond, MD, PhD

Herbert S. Gasser Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
Innate and Adaptive Host Immunity to Viral Infections

Key words
virology, microbial pathogenesis, immunology