Molecular Genetics and Genomics
Shin-ichiro Imai, MD, PhD
Professor
- Email: imaishin@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Understanding the molecular mechanism of aging and longevity in mammals
Key words
aging, longevity, hypothalamus, metabolism, NAD biosynthesis, Sirt1, NAMPT, NAD World
Sanjay Jain, MD, PhD
Associate Professor
- Email: sjain22@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Research summary
Interactions between the nervous and genitourinary systems during development, molecular basis for heterogeneity in progenitors and their lineage commitments in the GU tract, injury and regeneration using animal models, mechanisms of malformations using organoids from iPSCs
Key words
cell fate, gene expression, genomics, disease models, growth factor signaling, kidney, bladder, innervation, stem cells, organogenesis, nervous system development, birth defects
Aimee James, PhD, MPH
Associate Professor
- Email: aimeejames@wustl.edu
Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Research summary
Cancer prevention and control, health disparities and community-based research
Key words
Joanna Jankowsky, PhD
Professor
- Email: jankowsky@wustl.edu
Program affiliation
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Cellular and molecular pathogenesis of Alzheimer's disease
Key words
Alzheimer's disease, neurodegeneration, amyloid, tau, mouse models, risk factors, lysosome, gene therapy
Ali Javaheri, MD, PhD
Assistant Professor
- Email: ali.javaheri@wustl.edu
Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Key words
Peter Jin
Assistant Professor
- Email: jin810@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Human and Statistical Genetics
Research summary
We use human genetic, functional genomic, and bioinformatic approaches to understand the consequence of genetic variants underlying diseases
Key words
Functional genomics, bioinformatics, human genetics, data science, rare diseases, structural variation
Aaron Johnson, PhD
Associate Professor
- Email: anjohnson@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Immunology
Research summary
Molecular mechanisms of skeletal and cardiac muscle development and disease
Key words
muscle, congenital disease, organogenesis, gene discovery
Usheer Kanjee, PhD
Assistant Professor
- Email: kanjee@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Immunology
Molecular Genetics and Genomics
Research summary
Key words
Sana Karam, MD, PhD
James S McDonnell Professor & Head of the Department of Radiation Oncology
- Email: sanadkaram@wustl.edu
Program affiliation
Immunology
Cancer Biology
Computational and Systems Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Key words
tumor growth, metastasis, signaling mechanisms, immunology, cancer, B cells, Tregs
Andrew Kau, MD, PhD
Associate Professor
- Email: akau@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Molecular Genetics and Genomics
Computational and Systems Biology
Research summary
Microbial community-immune interactions in airway diseases and urogenital tract
Key words
microbiota; microbiome; mucosal immunity; asthma; allergy; atopy; urinary tract infection; pathogen colonization; metabolomics;