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Camillo Padoa-Schioppa, PhD

Professor

Program affiliation
Neurosciences

Research summary
Neurobiology of economic decisions

Key words
decision making, neuroeconomics, neurophysiology, computational neuroscience, prefrontal cortex

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Ben Palanca, MD, PhD, MSc

Associate Professor

Program affiliation
Neurosciences

Research summary
Dr. Palanca has NIH-funded investigations on acute confusion after cardiac surgery and leveraging the anesthetic propofol to modulate sleep to treat depression and cognitive impairment.

Key words
Anesthesia, delirium, sleep, surgery, electroencephalography, imaging, fMRI, consciousness, cognition, encephalopathy, depression, antidepressant

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Michael Paley, MD, PhD

Assistant Professor

Program affiliation
Immunology
Computational and Systems Biology
Neurosciences

Research summary
Mechanisms of inflammation in immune-privileged organs

Key words

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Thomas Papouin, PhD

Assistant Professor

Program affiliation
Neurosciences

Research summary
Mechanisms or neuron-glia interactions in health and disease

Key words
Astrocytes, Synapses, Neuromodulation, Behavior, Electrophysiology,

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Bhuvic Patel, MD

Assistant Professor

Program affiliation
Neurosciences
Cancer Biology
Computational and Systems Biology

Research summary
Our lab employs cutting-edge molecular biology techniques to investigate the genetic, epigenetic, and cellular alterations driving the initiation, progression, and therapeutic resistance of brain tumors.

Key words
brain tumors, systems biology, genetics, neurosurgery, neurooncology

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Guangyong Peng, MD, PhD

Professor

Program affiliation
Immunology
Cancer Biology
Neurosciences

Research summary
Understanding the role of immune system in the pathogenesis of cancer and age-related neurological disorders (Alzheimer's disease), and then to develop effective strategies for manipulation of immune cell fate and function for disease prevention and immunotherapy.

Key words
Senescent T cells, Regulatory T cells (Tregs), Dendritic cells (DCs), Tumor microenvironment, Alzheimer's disease, Cell metabolism, Toll-like receptors, Immunotherapy

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Susan Perlman, PhD

Associate Professor

Program affiliation
Neurosciences

Research summary

Key words

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Joel Perlmutter, MD

Professor

Program affiliation
Neurosciences

Research summary
Pharmacology, physiology and pathophysiology of basal ganglia and movement disorders

Key words
pathogenesis, neuroimaging, physiology, neurobiology, movement disorders, Parkinson disease, dystonia

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Benjamin Philip, PhD

Assistant Professor

Program affiliation
Neurosciences

Research summary
The interaction between hand dominance, brain lateralization, and rehabilitation following unilateral impairment such as stroke, amputation, or nerve injury

Key words

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Jennifer Phillips-Cremins, PhD

BJC Investigator and James S. McDonnell Professor

Program affiliation
Molecular Genetics and Genomics
Neurosciences
Computational and Systems Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology

Research summary
The Cremins lab integrates molecular and computational biology to elucidate how the genome’s structure-function relationship influences synaptic plasticity and neurophysiology during memory encoding and consolidation and how this goes awry in intractable neurological disorders.

Key words
chromatin, neuroepigenetics, 3D genome, synaptic plasticity, Alzheimer's, repeat expansion disorders, chromatin-synapse communication, neural connectome, organoids