Neurosciences
Joel Perlmutter, MD
Professor
- Email: perlmutterjoel@wustl.edu
Program affiliation
Neurosciences
Research summary
Pharmacology, physiology and pathophysiology of basal ganglia and movement disorders
Key words
pathogenesis, neuroimaging, physiology, neurobiology, movement disorders, Parkinson disease, dystonia
Jennifer Phillips-Cremins, PhD
BJC Investigator and James S. McDonnell Professor
- Email: jennifer.cremins@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Neurosciences
Computational and Systems Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
The Cremins lab integrates molecular and computational biology to elucidate how the genome’s structure-function relationship influences synaptic plasticity and neurophysiology during memory encoding and consolidation and how this goes awry in intractable neurological disorders.
Key words
chromatin, neuroepigenetics, 3D genome, synaptic plasticity, Alzheimer's, repeat expansion disorders, chromatin-synapse communication, neural connectome, organoids
Marco Pignatelli, MD
Assistant Professor
- Email: marco.pignatelli@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Research summary
Understanding the synaptic mechanisms by which emotional experiences lead to maladaptive plasticity and the impact of neurotherapeutic drugs on those maladaptive synaptic neuroadaptations
Key words
synaptic plasticity, Optogenetics, cell-type specific pharmacology, patch clamp electrophysiology, rapid-acting antidepressants, motivated behavior, drug addiction and affective disorders
Elizabeth Ann Pollina, PhD
Assistant Professor
- Email: pollina@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Molecular Mechanisms of Nervous System Longevity and Rejuvenation
Key words
epigenetics, nervous system, DNA repair, aging, rejuvenation
John Pruett, Jr., MD, PhD
Professor
- Email: pruettj@wustl.edu
Program affiliation
Neurosciences
Biomedical Informatics and Data Science
Research summary
The neuroscience of ASD, social cognition and comparative cognition
Key words
fcMRI, fMRI, infant, autism, face perception, visual attention, psychophysics, social cognition, comparative cognition
Marcus Raichle, MD
Professor
- Email: mraichle@wustl.edu
Program affiliation
Neurosciences
Research summary
Functional brain imaging with positron emission tomography and magnetic resonance
Key words
imaging, behavior, cognition, fMRI, PET
Baranidharan Raman, PhD
Associate Professor
- Email: barani@seas.wustl.edu
Program affiliation
Neurosciences
Computational and Systems Biology
Research summary
Systems analysis of neural information processing; bio-inspired sensors and algorithms
Key words
mathematical modeling, neurobiology, neurophysiology, sensory systems, smell, systems neuroscience
Maria Remedi, PhD
Professor
- Email: mremedi@wustl.edu
Program affiliation
Molecular Cell Biology
Neurosciences
Developmental Regenerative and Stem Cell Biology
Research summary
Channels: diabetes, obesity and brain disorders
Key words
Diabetes, disease, channels, brain, neurons, hormones, growth, death, obesity, physiology