Programs

Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science

Research summary
Mammalian gene expression: Regulation through mRNA editing and RNA stabilization

Key words
gene expression, RNA, cancer, mRNA editing, mRNA stability

Program affiliation
Molecular Genetics and Genomics

Research summary
Noninvasive characterization of heart function in patients with high blood pressure

Key words
imaging, hypertrophy, myocardial bloodflow

Program affiliation
Neurosciences
Molecular Cell Biology
Immunology
Biochemistry Biophysics and Structural Biology

Research summary
Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies

Key words
Parkinson disease, Lewy body dementia, REM sleep behavior disorder, synuclein, neurodegeneration, microglia, APOE, orexin

Program affiliation
Cancer Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics

Research summary
My lab is interested in understanding how dysregulation of the Core Binding Factor transcription factor promotes AML development

Key words
hematopoiesis, leukemia, AML, acute myeloid leukemia, CBF, RUNX1, CBFB, core binding factor

Program affiliation
Biomedical Informatics and Data Science
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Plant and Microbial Biosciences

Research summary
We integrate metabolic, movement, and community ecology to address core and applied ecological and evolutionary questions. Spanning diverse species and habitats, our research links individual physiology to global biodiversity patterns using theory, data, experiments, and field studies. We aim to understand ecological systems, including human impacts, to inform effective management and policy.

Key words
metabolism, movement ecology, community ecology, behavior, species interactions, human-nature interactions, biogeography, global change, computer vision, eco-informatics, complex systems, biodiversity, great river systems, ecological management

Program affiliation
Cancer Biology
Molecular Cell Biology
Immunology

Research summary
Molecular Mechanisms of Immune Regulation of Tumor Progression.

Key words
immunotherapy, breast cancer, pancreatic cancer, immunology, inflammation, metastasis, storm

Program affiliation
General

Research summary
Our lab uses murine stroke models and stroke patient samples to better understand ischemic stroke pathology.

Key words
Stroke platelet neutrophil neurology translational research

Program affiliation
Immunology
Cancer Biology
Molecular Cell Biology

Research summary
The DeSelm Lab focuses on engineering immune cells with chimeric antigen receptors (CARs) to better understand tumor-immune interactions and develop next generation therapies for cancer, Alzheimer's Disease, and other incurable conditions.

Key words
Immunotherapy, cancer, CAR T-cells, CAR-DC1

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
Innate and Adaptive Host Immunity to Viral Infections

Key words
virology, microbial pathogenesis, immunology, vaccines, therapeutics, antibody

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology

Research summary
Neural circuits in development and disease

Key words
axon regeneration, axon degeneration, neurodegeneration, glia, neuronal development and differentiation, neuroinflammation, neuroimmunology, synapse biology, drug screens, metabolism