Programs
Naomi Dirckx, PhD
Assistant Professor
- Email: dirckx@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Key words
Abhinav Diwan, MD, FACC, FAHA
Charlie W. Shaeffer, MD, Professor
- Email: adiwan@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Transcriptional regulation of lysosome machinery under stress
Key words
Lysosomes, Ischemia-reperfusion, cell death, autophagy, transcriptional regulation, metabolism
Ram Dixit, PhD
George and Charmaine Mallinckrodt Professor and Biology Department Chair
- Email: ramdixit@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Molecular mechanisms of cytoskeleton organization and function
Key words
cytoskeleton, molecular motors, cell morphogenesis, cell wall biogenesis, plant biology
Ian G. Dobbins, PhD
Professor
- Email: idobbins@wustl.edu
Program affiliation
Neurosciences
Research summary
Interaction of Episodic Memory and Decision-Making Using fMRI and behavioral methods
Key words
Tamara L. Doering, MD, PhD
Alumni Endowed Professor
- Email: doering@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Research summary
Biology and pathogenesis of the pathogenic fungus Cryptococcus neoformans
Key words
biochemistry, biosynthetic pathways, cell biology, eukaryotic pathogen, gene regulation, genomic variants, glycobiology, host-pathogen interactions, microbial pathogenesis, pathogenic fungi, sterol transport, yeast
Anita Donlic, PhD
Assistant Professor
- Email: donlic@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Cancer Biology
Molecular Genetics and Genomics
Computational and Systems Biology
Research summary
Cells are not just bags of molecules - they organize their biochemistry in space, often using dynamic compartments called biomolecular condensates. Our lab is asking fundamental questions about the role of condensates in biology, such as: how do condensate environments influence RNA recognition and metabolism? How do they alter the activity of therapeutics? And how do they contribute to oncogenic cell states? We do this using interdisciplinary approaches spanning chemical biology, quantitative cell microscopy, in vitro biophysics, and machine learning. We hope to ultimately uncover how subcellular organization shapes cellular function and how these principles can be harnessed therapeutically.
Key words
condensates, RNA, chemical biology, therapeutics, microscopy, cancer
Nico U.F. Dosenbach, MD, PhD
David M. and Tracy S. Holtzman Professor
- Email: dosenbachn@wustl.edu
Program affiliation
Neurosciences
Research summary
Functional network plasticity in development and brain injury
Key words
functional networks, plasticity, brain injury, development, perinatal stroke, MRI, resting state
Joseph D. Dougherty, PhD
Professor
- Email: jdougherty@wustl.edu
Program affiliation
Neurosciences
Molecular Genetics and Genomics
Computational and Systems Biology
Human and Statistical Genetics
Research summary
Human Psychiatric Genetics, Mouse Models, Cell Type Specific Gene Expression Profiling, Translation, Astrocytes.
Key words
autism, gene expression profiling, genetics, genomics, mouse models, neurobiology, astrocytes, translation regulation
Lizzy Draganova
Assistant Professor
- Email: draganova@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Our lab investigates how human herpesviruses replicate and assemble into new particles using interdisciplinary tools in virology, chemistry, and biophysics.
Key words
herpesvirus, assembly, capsid, biophysics, virology, biochemistry
Bettina F. Drake, PhD, MPH
Assistant Professor
- Email: drakeb@wustl.edu
Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Cancer Biology
Research summary
Identifying preventive strategies to reduce cancer disparities
Key words