Programs

Program affiliation
Cancer Biology
Biochemistry Biophysics and Structural Biology

Research summary

Key words

Program affiliation
Biochemistry Biophysics and Structural Biology

Research summary
Development and application of mass spectrometry in biophysics, biochemistry, and medicine

Key words
amyloid beta biophysics, biochemistry, biophysics, mass spectrometry, protein-protein interaction, protein structure,

Program affiliation
General

Research summary
The molecular mechanisms through which biologic membranes participate in cellular activation processes

Key words
phospholipase A2, diabetes, obesity, receptor, myocardial ischemia, lipid metabolism

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Neurosciences
Computational and Systems Biology
Molecular Cell Biology

Research summary
We work on what induces the inner ear in the first place, how the sensory organs of the ear acquire their exquisite pattern, and whether it will ever be possible to regenerate the sensory hair cells of the inner ear in the deaf and hard-of-hearing.

Key words
inner ear, development, regeneration, sensory neuroscience, balance, deafness, embryo, transcription factors, epigenetics, tunicates, squid

Program affiliation
Biomedical Informatics and Data Science
Human and Statistical Genetics
Computational and Systems Biology

Research summary
Statistical genetics and bioinformatics, high-dimensional data analysis and complex systems modeling, developing novel methodologies for detecting complex disease genes and characterizing their function

Key words
genetic epidemiology, statistical genetics

Program affiliation
Neurosciences
Molecular Cell Biology
Immunology

Research summary
We develop innovative magnetic resonance (MR) and position emission tomography (PET) imaging approaches to monitor neuroinflammation, neurodegeneration and repair mechanisms in neurological disorders

Key words
Metabolic imaging, hyperpolarized 13C MRI, positron tomography emission (PET) imaging, neurological disorders, cell tracking, multiple sclerosis, microglia, myelin, immune cells

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Immunology

Research summary
Application of stem cells and mechanobiology in the onset, progression, and treatment of osteoarthritis and other joint diseases.

Key words
cartilage, obesity, osteoarthritis, mechanobiology, bioengineering, stem cells, iPSCs

Program affiliation
Biomedical Informatics and Data Science

Research summary

Key words

Program affiliation
Neurosciences
Cancer Biology
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology

Research summary
Leveraging neurogenetic disorders to study normal brain development, cancer, and autism

Key words
pediatric brain cancer, brain development, neuroimmunology, cancer neuroscience, autism, hiPSC engineering, genetically engineered mice

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
Understanding how the extracellular matrix (ECM) contributes to normal arterial development and how its disruptionleads to abnormal vascular development and disease

Key words
Vascular biology, extracellular matrix, elastin, aneurysms, hypertension