Programs
David H. Gutmann, MD, PhD
Donald O. Schnuck Family Professor
- Email: gutmannd@wustl.edu
Program affiliation
Neurosciences
Cancer Biology
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Research summary
The Gutmann laboratory is dedicated to understanding why brain tumors develop in children and young adults. Specifically, we focus on neurofibromatosis type 1 (NF1), a genetic condition in which affected children and adults develop brain tumors, attention deficit, and autism.
Key words
neurogenetics, , hiPSC engineering (organoids), genetically engineered mice, pediatric brain cancer, cancer immunology, cancer neuroscience
Carmen Halabi, MD, PhD
Associate Professor
- Email: chalabi@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Understanding how the extracellular matrix (ECM) contributes to normal arterial development and how its disruptionleads to abnormal vascular development and disease
Key words
Vascular biology, extracellular matrix, elastin, aneurysms, hypertension
Kathleen B. Hall, PhD
Professor
- Email: hallkathleen@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
We study RNA folding and RNA binding to proteins
Key words
RNA, NMR, RNA:protein interactions, fluorescence, thermodynamics
Dennis E. Hallahan, MD
Professor and Head of the Department of Radiation Oncology
- Email: dhallahan@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Research summary
The mechanisms of cell death in normal tissues during cancer therapy
Key words
cancer, cell death, drug delivery, radiation, signal transduction
Gabriel Haller, PhD
Associate Professor
- Email: ghaller@wustl.edu
Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Computational and Systems Biology
Neurosciences
Research summary
Genetic underpinnings of neurological/neurosurgical disorders
Key words
rare variants, Chiari I malformation, human genetics, neurosurgery, Deep Mutation Scanning, Mutagenesis, Limb-girdle muscular dystrophy
Claudia Han, PhD
Assistant Professor
- Email: claudiah@wustl.edu
Program affiliation
Immunology
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Neurosciences
Research summary
The Han lab investigates microglia and brain macrophage phenotypes in neurodevelopmental and neurodegenerative contexts through the lens of epigenomics and transcriptomics.
Key words
microglia, neurodevelopment, epigenetics, transcriptomics, neurodegeneration
Edward B. Han, PhD
Assistant Professor
- Email: ehan23@wustl.edu
Program affiliation
Neurosciences
Research summary
Learning-related hippocampal network activation
Key words
Learning, memory, behavior, virtual reality, in vivo two-photon imaging, dopamine, modeling, systems neuroscience
Scott A. Handley, PhD
Professor
- Email: shandley@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Immunology
Research summary
Key words
Richard A. Harbison, MD, MS
Assistant Professor
- Email: hrichard@wustl.edu
Program affiliation
Immunology
Computational and Systems Biology
Research summary
Studying effects of dysregulated nutrients in the tumor microenvironment on anti-tumor immunity.
Key words
immunometabolism, tumor immunology, polyamine transport
Simon Haroutounian, PhD, MSc
Assistant Professor
- Email: sharout@wustl.edu
Program affiliation
Neurosciences
Research summary
Dr. Haroutounian studies neuropathic pain with a focus on determining individual predictors of treatment response to analgesic pharmacotherapy.
Key words