Programs

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology

Research summary
Molecular pathogenesis of Mycobacterium tuberculosis

Key words
bacteria, gene regulation, molecular genetics, microbiology, pathogenesis, transcription, infectious disease, innate immunity

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
Investigate the genetic and environmental factors that underlie the mechanistic basis for the heterogeneity in outcomes in response to infection

Key words

Program affiliation
Cancer Biology

Research summary
Glioblastoma metabolism, mechanisms of immunosupression, and the development of novel gene-regulatory and immunostimulatory nanotechnologies

Key words

Program affiliation
Neurosciences

Research summary
Sensorimotor integration; spinal cord neural networks; turtle hindlimb motor output

Key words
behavior, central pattern generators, neurobiology, physiology, spinal cord

Program affiliation
General

Research summary
We are interested in the epithelial response to injury in the intestine and in mucosal immununology in the intestine.

Key words
apoptosis, epithelial cells, immunology, inflammation, innate immunity, prostaglandin, radiation

Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology

Research summary
Examining the role the tumor microenvironment plays in immune modulation, tumor development, metastasis and dormancy

Key words
aging, cancer, microenvironment, RNAi, senescence, telomere

Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Computational and Systems Biology
Biomedical Informatics and Data Science

Research summary
We use multiomic approaches to discover mechanisms underlying cardiovascular disease and leverage these insights to identify new drug targets.

Key words
Human genetics; cardiovascular disease

Program affiliation
Developmental Regenerative and Stem Cell Biology

Research summary
Work in our lab focuses on the role of insulin resistance in human metabolic diseases. To accomplish this, we focus our efforts on patients with severe insulin resistance syndromes.

Key words
Insulin Resistance, Atypical Diabetes, Pediatric Endocrinology, FGF21, Fibroblast Growth factors

Program affiliation
General

Research summary
Computational biology, bioinformatics, protein-DNA interactions, gene regulation

Key words
computational biology, genome analysis, gene expression, mathematical modeling

Program affiliation
Neurosciences

Research summary
To understand and develop treatments for cerebrospinal fluid circulation disorders during development, including neonatal post-hemorrhagic hydrocephalus

Key words