Mario F. Feldman, Ph.D.

Associate Professor
Molecular Microbiology

Molecular Microbiology and Microbial Pathogenesis Program

  • 314-747-4473

  • 314-362-1262

  • 8230

  • mfeldman@wusm.wustl.edu

  • Microbial glycobiology and its exploitation for vaccine development

Research Abstract:

My lab is focused in microbial glycobiology and its exploitation for vaccine development. We also work on outer membrane vesicles (OMV) biogenesis. We have a particular interest in Acinetobacter baumannii virulence and survival mechanisms.

Selected Publications:

Ciocchini AE, Rey Serantes DA., Melli LJ, Iwashkiw JA, Deodato B, Wallach J, Feldman MF, Ugalde JE, and Comerci DJ. (2013) Development and Validation of a Novel Diagnostic Test for Human Brucellosis Using a Glyco-engineered Antigen Coupled to Magnetic Beads. PLoS Negl. Trop. Dis. 7(2): e2048.

Iwashkiw JA, Vozza NF, Kinsella RL, Feldman MF. Pour some sugar on it: the expanding world of bacterial protein O-linked glycosylation. Molecular Microbiology 2013. 89:14-28.

Musumeci MA, Hug I, Scott NE, Ielmini MV, Foster LJ, Wang PG, and Feldman MF. (2013) In vitro activity of Neisseria meningitidis PglL O-oligosaccharyltransferase with diverse synthetic lipid donors and a UDPactivated
sugar. J. Biol. Chem. 288:10578-10587.

Lees-Miller R, Iwashkiw J, Scott NE, Seper A, Vinogradov E, Schild S, and Feldman MF. (2013) A common pathway for O-linked protein-glycosylation and synthesis of capsule in Acinetobacter baumannii. Mol. Microbiol. 89:816-830.

Musumeci MA, Faridmoayer A, Watanabe Y, and Feldman MF. (2014) Evaluating the role of conserved amino acids in bacterial O-oligosaccharyltransferases by in vivo, in vitro, and limited proteolysis assays. Glycobiology. 24:39-50.

Last Updated: 7/22/2015 2:59:16 PM

Back To Top

Follow us: