Faculty

DBBS mentors and educators are key to our training mission. Those who serve as primary mentors are DBBS Program Members, and others who participate in the educational mission are General Members. Learn about DBBS Faculty Membership »

To provide a supportive learning environment for our trainees, many DBBS-affiliated faculty have completed eight or more hours of CIMER-based mentorship training with a trained facilitator, as indicated below with a profile badge.

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Find faculty of interest by entering a name, program or expertise keyword in the search bar; selecting a PhD program from the drop-down menu; or selecting the last name initial from the A-Z filter.

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Angela Hirbe, MD, PhD

Associate Professor

Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
Utilization of genomic information from sarcomas to better understand the pathogenesis of these tumors and to identify biomarkers and therapeutic targets for these aggressive cancers.

Key words
sarcoma, metastasis, genomics, cell signalling, NF1, MPNST

Keiko Hirose, MD

Associate Professor

Program affiliation
Neurosciences

Research summary
Innate immunity in the inner ear

Key words
inflammation, inner ear, cochlear injury, monocytes, macrophages, blood labyrinth barrier

Alex Holehouse, PhD

Associate Professor

Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Molecular Cell Biology
Plant and Microbial Biosciences

Research summary
Understand how function is encoded into disordered sequences using a combination of computational and experimental approaches

Key words
Disordered proteins, IDPs, IDRs, phase transitions, emergence, deep learning, AI, bird-themed software packages

David Holtzman, MD

Barbara Burton and Reuben M. Morriss III Distinguished Professor

Program affiliation
Neurosciences
Molecular Cell Biology

Research summary
Cellular and Molecular studies of Alzheimer’s disease

Key words
amyloid, tau, antibodies, apolipoprotein E, Alzheimer’s disease, neurodegeneration, neurobiology

Michael Holtzman, MD

Selma and Herman Seldin Professor

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology

Research summary
New drugs for post-viral and related types of disease

Key words
drug discovery, innate immunity, epithelial stem cells, viruses, respiratory airway disease

Timothy Holy, PhD

Alan A. and Edith L. Wolff Professor

Program affiliation
Neurosciences
Computational and Systems Biology

Research summary
Sensory processing and plasticity (olfaction), large-population calcium imaging, computation, social communication

Key words
calcium imaging, physiology, mathematical modeling, behavior, neurobiology, smell, olfaction, pheromones, neuroendocrine, circuits

Amjad Horani, MD

Associate Professor

Program affiliation
Molecular Cell Biology

Research summary
Our lab studies airway and motile cilia biology and investigates the effects of mutations on cilia function

Key words
cilia, PCD, airway, lung

Ashley Housten, OTD, OTR/L, MSCI, MPA

Associate Professor

Program affiliation
Biomedical Informatics and Data Science
Molecular Genetics and Genomics

Research summary

Key words
shared decision making, health equity, implementation science

Paul Hruz, PhD, MD

Associate Professor

Program affiliation
Molecular Cell Biology

Research summary
Structural Biology and Regulation of Glucose Transport; Molecular Mechanisms Leading to Insulin Resistance

Key words
protein structure, glucose transport, diabetes, AIDS, HIV therapy, membrane protein, structural biology, heart, affinity labeling, drug design

Chyi-Song Hsieh, MD, PhD

Professor

Program affiliation
Cancer Biology
Immunology

Research summary
Understanding T cell tolerance to self and non-self

Key words
autoimmunity, immunology, lymphocyte, regulatory T cell, tolerance, mucosal immunology

Feng Sheng Hu, PhD

Richard G. Engelsmann Dean of Arts & Sciences and Lucille P. Markey Distinguished Professor

Program affiliation
Plant and Microbial Biosciences
Ecology and Evolutionary Biology

Research summary
Understanding patterns and mechanisms of long-term ecosystem dynamics under changing climatic conditions

Key words
ecosystem ecology, quaternary paleoecology, climatic change and biotic response, soil and sediment biogeochemistry

Andrew Huang, MD, MPH

Professor

Program affiliation
General

Research summary
Corneal epithelial wound healing, neovascularization and stromal dystrophies

Key words
amyloid, epithelial cells, protein folding, siRNA, stem cells, vision

Cheng Huang, PhD

Assistant Professor

Program affiliation
Neurosciences
Molecular Cell Biology
Computational and Systems Biology

Research summary
Our lab deciphers how fruit flies learn, memorize, and make decisions using state-of-the-art optical imaging techniques

Key words
Voltage imaging, computational modeling, learning system, memory processing, Drosophila melanogaster

Eric Huang, MD, PhD

Joseph M. Davie Distinguished Professor and Chair of the Department of Pathology and Immunology

Program affiliation
Immunology
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics

Research summary

Key words

Henry Huang, PhD

Associate Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis

Research summary
Molecular biology of Sindbis virus; antiviral drug design; monocyte differentiation

Key words
RNA, virology, genome analysis, evolution, antiviral targeting

James Huettner, PhD

Associate Professor Retired

Program affiliation
General

Research summary
Glutamate receptors, synaptic transmission and stem cell differentiation

Key words
stem cells, differentiation, synapse biology, receptor, ion channel

Mark Huffman

Professor

Program affiliation
General

Research summary
I seek to improve global cardiovascular health across the spectrum of disease prevention through rigorous research, including the development, adaptation, and implementation of evidence-based interventions, practices, and policies into routine practice at scale.

Key words
global cardiovascular health, dissemination and implementation science, trials, health systems, policy

Scott Hultgren, PhD

Helen L. Stoever Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology

Research summary
Interdisciplinary approach combining genetics, genomics, biochemistry, structural biology, high-resolution imaging, animal models, clinical studies and combinatorial chemistry to determine key aspects of bacterial pathogenesis and apply our knowledge to development of new therapeutics.

Key words
antibiotic-sparing therapeutics, host-pathogen interactions, bacterial pathogenesis, drug and vaccine development, multi-drug resistant E. coli, MRSA, Enterococcus, Acinetobacter, Klebsiella, urinary tract infections (UTI)

Benjamin Humphreys, MD, PhD

Joseph Friedman Professorof Renal Didease

Program affiliation
Developmental Regenerative and Stem Cell Biology
Computational and Systems Biology

Research summary
Define cell hierarchies in kidney injury and repair and thereby identify the critical cell types in kidney repair and fibrosis

Key words
Stem cells, regenerative medicine, scRNA-seq, scATAC-seq, spatial transcriptomics, fibrosis, gene editing, iPS cells

David Hunstad, MD

Arnold W. Strauss, MD, Endowed Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis

Research summary
Sex differences, virulence factors, and novel therapeutics in E. coli urinary tract infections

Key words
bacterial pathogenesis, Escherichia coli, host-pathogen interactions, innate immunity, novel therapeutics, urinary tract infection, kidney, pyelonephritis, sex differences

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