DBBS mentors and educators are key to our training mission. Those who serve as primary mentors are DBBS Program Members, and others who participate in the educational mission are General Members. Learn about DBBS Faculty Membership »
To provide a supportive learning environment for our trainees, many DBBS-affiliated faculty have completed eight or more hours of CIMER-based mentorship training with a trained facilitator, as indicated below with a profile badge.
Find faculty of interest by entering a name, program or expertise keyword in the search bar; selecting a PhD program from the drop-down menu; or selecting the last name initial from the A-Z filter.
Lavinia Sheets, PhD
Associate Professor
- Email: sheetsl@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
We use zebrafish as a model for human hearing and balance with the goal of protecting and repairing inner ears from damage.
Key words
zebrafish, sensory neuroscience, hearing, balance, synaptic physiology, regeneration
Chen Shen, PhD
Assistant Professor
- Email: shenc@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Understand the structural mechanisms of host-pathogen interactions and the inflammasome signaling
Key words
structural biology, innate immunity, pattern recognition receptors, immune recognition, inflammasomes
Jie Shen, PhD
Associate Professor
- Email: shen.j@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Focused on injury, repair, and regeneration of musculoskeletal tissues with the goal to understand the progenitor cell population, signals, and role of inflammation on tissue injury and regeneration at the cellular and molecular level
Key words
Mengcheng Shen
Assistant Professor
- Email: shen.m@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Immunology
Neurosciences
Research summary
My research program integrates cardiovascular physiology, stem cell biology, developmental biology, functional genomics, and cardio-oncology to investigate molecular mechanisms of congenital and acquired cardiovascular diseases. My laboratory specializes in developing innovative protocols for generating authentic cardiovascular cell types from human induced pluripotent stem cells (iPSCs), advancing cardiovascular precision medicine. We aim to bridge basic science and clinical translation through disease modeling, therapeutic target identification, and adverse outcome prevention.
Key words
iPSC, CRISPR, organoid, cardiovascular, precision medicine, cardio-oncology
Joshua Shimony, MD, PhD
Professor
- Email: shimonyj@wustl.edu
Program affiliation
Neurosciences
Research summary
Translational Brain MRI Clinical Applications; Neurophysiology Modeling Using MRI Methods
Key words
brain, imaging, magnetic resonance imaging, fMRI, DTI, perfusion, mathematical modeling
Marwan Shinawi, MD
Professor
- Email: mshinawi@wustl.edu
Program affiliation
General
Research summary
Clinical genomics and the application of exome and genome sequencing as well as microarray analysis for disease gene discovery
Key words
genomic medicine, disease gene discovery, metabolic disorders, and skeletal dysplasias
Leonid Shmuylovich, MD,PhD
Assistant Professor
- Email: shmuylol@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science
Research summary
Develop optical imaging technologies that address clinical problems with a focus on dermatology
Key words
dermatology imaging engineering pigmentation global heath
Kooresh Shoghi, PhD
Professor
- Email: shoghik@wustl.edu
Program affiliation
Computational and Systems Biology
Cancer Biology
Biomedical Informatics and Data Science
Neurosciences
Research summary
I have multidisciplinary research interests spanning disease biology, engineering, imaging sciences, and informatics. Our work integrates computational imaging, artificial intelligence, and clinical/translational medicine to discover and validate quantitative imaging biomarkers and to define therapeutic endpoints in cancer and other diseases.
Key words
Computational medicine, cancer, systems biology and quantitative imaging
Monica Shokeen, PhD
Associate Professor
- Email: shokeenm@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Immunology
Research summary
Development and evaluation of small- and macro-molecular agents for multi-modal molecular imaging of cancer and cardiovascular diseases
Key words
L. David Sibley, PhD
Professor
- Email: sibley@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology
Research summary
Cellular and molecular basis of intracellular parasitism by protozoan parasites
Key words
cell-signaling, kinases, transcription, chromatin, pathogenesis, genetics, genomics, chemical biology, innate immunity
Jonathan Silva, PhD
Associate Professor
- Email: jonsilva@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Computational and Systems Biology
Biomedical Informatics and Data Science
Research summary
Engineering to help cardiac arrhythmia patients feel better and live longer.
Key words
Bioelectricity, Arrhythmias, Modeling, Molecular Imaging, Electrophysiology, Induced Pluripotent Stem Cells
Matthew Silva, PhD
Professor
- Email: silvam@wustl.edu
Program affiliation
Molecular Cell Biology
Human and Statistical Genetics
Research summary
Skeletal mechanobiology; bone strength; osteoporosis; bone fracture, repair & regeneration
Key words
bone mechanics, bone biology, injury, mechanotransduction, mouse models, osteoporosis
Jessica Silva-Fisher, PhD
Assistant Professor
- Email: silvajm@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Long non-coding RNAs and RNA modifications in cancer metastasis and aggressive disease
Key words
Cancer metastasis, multiple myeloma, breast cancer, long non-coding RNAs, RNA modifications, genomics, advanced sequencing, epitranscriptomics
Srikanth Singamaneni, PhD
Associate Professor
- Email: singamaneni@WUSTL.EDU
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Plasmonic biosensors and biomimetic sensors
Key words
biomimetic sensors, plasmonic biosensors, nanostructures, transduction platforms
Nathan Singh, MD, MS
Associate Professor
- Email: nathan.singh@wustl.edu
Program affiliation
Immunology
Cancer Biology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Research summary
Understanding how synthetic antigen receptors direct T cell function and dysfunction in the treatment of blood cancers
Key words
CAR T cell therapy, immunotherapy for cancer, T cell signaling, T cell dysfunction, lineage decisions
James Skeath, PhD
Professor
- Email: jskeath@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Neurosciences
Research summary
Genetic analysis of neural and muscular development in the Drosophila embryo
Key words
development, neurobiology, cell signaling
R. Keith Slotkin, PhD
Full Member and Principal Investigator
- Email: r.keith@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Genetics and Genomics
Research summary
Investigating how plant cells determine which fragments of DNA should be expressed (like genes), and which should be targeted for repression and not allowed to express
Key words
transposable element, epigenetics, DNA methylation, chromatin, transgene silencing
Adam Smith, PhD
Associate Scientist
- Email: adamsmith@wustl.edu
Program affiliation
Ecology and Evolutionary Biology
Research summary
Key words
Christopher Smyser, MD
Professor
- Email: smyserc@wustl.edu
Program affiliation
Neurosciences
Research summary
Investigating the effects of prematurity and other modifiable clinical and environmental risk factors on neurodevelopmental outcomes in high-risk pediatric populations
Key words
Neurodevelopment; neonate; prematurity; psychopathology; brain injury; MRI; structural connectivity; functional connectivity
Lawrence Snyder, MD, PhD
Professor
- Email: larry@eye-hand.wustl.edu
Program affiliation
Neurosciences
Research summary
Information processing in the cerebral cortex
Key words
behavior, cognition, computational biology, eye-hand coordination, neurophysiology, systems neuroscience