Faculty

DBBS mentors and educators are key to our training mission. Those who serve as primary mentors are DBBS Program Members, and others who participate in the educational mission are General Members. Learn about DBBS Faculty Membership »

To provide a supportive learning environment for our trainees, many DBBS-affiliated faculty have completed eight or more hours of CIMER-based mentorship training with a trained facilitator, as indicated below with a profile badge.

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Find faculty of interest by entering a name, program or expertise keyword in the search bar; selecting a PhD program from the drop-down menu; or selecting the last name initial from the A-Z filter.

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Jeffrey Haspel, MD, PhD

Associate Professor

Program affiliation
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology

Research summary
Understand the impact of time as a biological variable in the development of critical illness such as sepsis, respiratory failure and chronic inflammatory lung disease

Key words

Xueyan He, PhD

Assistant Professor

Program affiliation
Cancer Biology
Immunology

Molecular Cell Biology

Research summary
Advancing knowledge of the mechanisms responsible for colorectal tumor progression, with a specific focus on Stress and its influence on the Tumor Microenvironment.

Key words
Tumor Microenvironment, Stress

Denise Head, PhD

Professor

Program affiliation
Neurosciences

Research summary
Cognitive neuroscience of aging

Key words
aging, Alzheimer’s disease, cognition, imaging, structure-function relations

Andrew Heath, DPhil

Spencer T. Olin Professor of Psychology

Program affiliation
Human and Statistical Genetics
Ecology and Evolutionary Biology
Biomedical Informatics and Data Science

Research summary
Genetic studies of alcoholism, smoking and drug dependence, depression, suicidality and anxiety disorders, personality disorders, and methodological research in genetic epidemiology

Key words
substance abuse, development, modeling, psychiatry, quantitative genetics

Jennifer Heemstra, PhD

Charles Allen Thomas Professor and Chair of the Department of Chemistry

Program affiliation
Biochemistry Biophysics and Structural Biology

Research summary
Utilization of nucleic acid molecular recognition and self-assembly to generate functional architectures for biosensing and bioimaging

Key words
Chemical Biology, Molecular Recognition, Biomolecular Assembly, Nucleic Acids, Biosensors, Cellular Imaging, RNA Editing, Biomaterials

Lamees Hegazy, PhD

Associate Professor

Program affiliation
General

Research summary
My research centers on defining how the dynamic conformational landscape of drug targets governs ligand binding, selectivity, and downstream signaling. Using integrated approaches—including molecular dynamics simulations, pharmacophore modeling, and virtual screening—I identify and characterize novel modulators for several targts. These studies uncover previously unrecognized binding pockets, reveal mechanisms of ligand-induced activation or inhibition

Key words

Jason Held, PhD

Assistant Professor

Program affiliation
Molecular Cell Biology
Cancer Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science

Research summary
Redox biochemistry in cell signaling and disease, Proteomics

Key words
proteomics, post-translational modification, cysteine, redox, mass spectrometry, oxidation

Jeffrey Henderson, MD, PhD

Professor

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Biochemical interactions between humans and bacteria in health and disease

Key words
bacterial pathogenesis, host-pathogen interactions, iron, mass spectrometry, medicinal chemistry, metabolomics

Keith Hengen, PhD

Associate Professor

Program affiliation
Neurosciences
Computational and Systems Biology
Molecular Cell Biology

Research summary
We take a “big data” approach to understanding the self-organization of neurons and networks in behaving animals.

Key words
Homeostatic plasticity, behavior, neurodegeneration, self-organization, emergence, learning, computational, computation, modeling

Andreas Herrlich, MD, PhD

Associate Professor

Program affiliation
Molecular Cell Biology

Research summary
We aim to identify cellular and molecular mechanisms in the novel and rapidly expanding field of interorgan crosstalk in health and disease.

Key words

Tamara Hershey, PhD

Professor

Program affiliation
Neurosciences

Research summary
Clinical neuroscience of diabetes and related diseases

Key words
neuroimaging, diabetes, hyperglycemia, hypoglycemia, Wolfram Syndrome, Parkinson disease, cognition, mood

Brett Herzog, MD,PhD

Assistant Professor

Program affiliation
Cancer Biology
Immunology

Research summary

Key words

Erik Herzog, PhD

Viktor Hamburger Distinguished Professor

Program affiliation
Neurosciences
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Biomedical Informatics and Data Science

Research summary
Molecular, cellular and circuit analysis of circadian rhythms in mammals

Key words
neurobiology, behavior, imaging, circadian rhythm, glia, brain cancer, potassium channels, neuropeptides, astrocytes, glioblastoma, cancer, developmental biology, computational modeling

John Heuser, MD

Professor Emeritus of Cell Biology and Physiology

Program affiliation
General

Research summary
Electron microscopy of cells and molecules

Key words
cell membrane, cytoskeleton, endocytosis, electron microscopy, extracellular matrix

Naoki Hiratani, PhD

Assistant Professor

Program affiliation
Neurosciences
Computational and Systems Biology
Biomedical Informatics and Data Science

Research summary
Understanding the learning mechanisms of the brain from theoretical and computational perspectives

Key words
Computational neuroscience, Synaptic plasticity, Olfaction, Deep learning

Angela Hirbe, MD, PhD

Associate Professor

Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
Utilization of genomic information from sarcomas to better understand the pathogenesis of these tumors and to identify biomarkers and therapeutic targets for these aggressive cancers.

Key words
sarcoma, metastasis, genomics, cell signalling, NF1, MPNST

Keiko Hirose, MD

Associate Professor

Program affiliation
Neurosciences

Research summary
Innate immunity in the inner ear

Key words
inflammation, inner ear, cochlear injury, monocytes, macrophages, blood labyrinth barrier

Alex Holehouse, PhD

Associate Professor

Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Molecular Cell Biology
Plant and Microbial Biosciences

Research summary
Understand how function is encoded into disordered sequences using a combination of computational and experimental approaches

Key words
Disordered proteins, IDPs, IDRs, phase transitions, emergence, deep learning, AI, bird-themed software packages

David Holtzman, MD

Andrew B. and Gretchen P. Jones Professor

Program affiliation
Neurosciences
Molecular Cell Biology

Research summary
Cellular and Molecular studies of Alzheimer’s disease

Key words
amyloid, tau, antibodies, apolipoprotein E, Alzheimer’s disease, neurodegeneration, neurobiology

Michael Holtzman, MD

Selma and Herman Seldin Professor

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology

Research summary
New drugs for post-viral and related types of disease

Key words
drug discovery, innate immunity, epithelial stem cells, viruses, respiratory airway disease

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