DBBS mentors and educators are key to our training mission. Those who serve as primary mentors are DBBS Program Members, and others who participate in the educational mission are General Members. Learn about DBBS Faculty Membership »
To provide a supportive learning environment for our trainees, many DBBS-affiliated faculty have completed eight or more hours of CIMER-based mentorship training with a trained facilitator, as indicated below with a profile badge.
Find faculty of interest by entering a name, program or expertise keyword in the search bar; selecting a PhD program from the drop-down menu; or selecting the last name initial from the A-Z filter.
Leonid Shmuylovich, MD,PhD
Assistant Professor
- Email: shmuylol@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science
Research summary
Develop optical imaging technologies that address clinical problems with a focus on dermatology
Key words
dermatology imaging engineering pigmentation global heath
Kooresh Shoghi, PhD
Professor
- Email: shoghik@wustl.edu
Program affiliation
Computational and Systems Biology
Cancer Biology
Biomedical Informatics and Data Science
Neurosciences
Research summary
I have multidisciplinary research interests spanning disease biology, engineering, imaging sciences, and informatics. Our work integrates computational imaging, artificial intelligence, and clinical/translational medicine to discover and validate quantitative imaging biomarkers and to define therapeutic endpoints in cancer and other diseases.
Key words
Computational medicine, cancer, systems biology and quantitative imaging
Monica Shokeen, PhD
Associate Professor
- Email: shokeenm@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Immunology
Research summary
Development and evaluation of small- and macro-molecular agents for multi-modal molecular imaging of cancer and cardiovascular diseases
Key words
L. David Sibley, PhD
Professor
- Email: sibley@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology
Research summary
Cellular and molecular basis of intracellular parasitism by protozoan parasites
Key words
cell-signaling, kinases, transcription, chromatin, pathogenesis, genetics, genomics, chemical biology, innate immunity
Jonathan Silva, PhD
Associate Professor
- Email: jonsilva@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Computational and Systems Biology
Biomedical Informatics and Data Science
Research summary
Engineering to help cardiac arrhythmia patients feel better and live longer.
Key words
Bioelectricity, Arrhythmias, Modeling, Molecular Imaging, Electrophysiology, Induced Pluripotent Stem Cells
Matthew Silva, PhD
Professor
- Email: silvam@wustl.edu
Program affiliation
Molecular Cell Biology
Human and Statistical Genetics
Research summary
Skeletal mechanobiology; bone strength; osteoporosis; bone fracture, repair & regeneration
Key words
bone mechanics, bone biology, injury, mechanotransduction, mouse models, osteoporosis
Jessica Silva-Fisher, PhD
Assistant Professor
- Email: silvajm@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Long non-coding RNAs and RNA modifications in cancer metastasis and aggressive disease
Key words
Cancer metastasis, multiple myeloma, breast cancer, long non-coding RNAs, RNA modifications, genomics, advanced sequencing, epitranscriptomics
Gary Silverman, MD, PhD
Harriet B Spoehrer Professor and Head of the Department of Pediatrics
- Email: gsilverman@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
The cellular response to life threatening human diseases.
Key words
serpins, cell death, lysosomes, necrotizing enterocolitis, C. elegans, proteases, protein misfolding, alpha-1 antitrypsin deficiency, drug discovery
Srikanth Singamaneni, PhD
Associate Professor
- Email: singamaneni@WUSTL.EDU
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Plasmonic biosensors and biomimetic sensors
Key words
biomimetic sensors, plasmonic biosensors, nanostructures, transduction platforms
Nathan Singh, MD, MS
Associate Professor
- Email: nathan.singh@wustl.edu
Program affiliation
Immunology
Cancer Biology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Research summary
Understanding how synthetic antigen receptors direct T cell function and dysfunction in the treatment of blood cancers
Key words
CAR T cell therapy, immunotherapy for cancer, T cell signaling, T cell dysfunction, lineage decisions
James Skeath, PhD
Professor
- Email: jskeath@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Neurosciences
Research summary
Genetic analysis of neural and muscular development in the Drosophila embryo
Key words
development, neurobiology, cell signaling
R. Keith Slotkin, PhD
Full Member and Principal Investigator
- Email: r.keith@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Genetics and Genomics
Research summary
Investigating how plant cells determine which fragments of DNA should be expressed (like genes), and which should be targeted for repression and not allowed to express
Key words
transposable element, epigenetics, DNA methylation, chromatin, transgene silencing
Adam Smith, PhD
Associate Scientist
- Email: adamsmith@wustl.edu
Program affiliation
Ecology and Evolutionary Biology
Research summary
Key words
Christopher Smyser, MD
Professor
- Email: smyserc@wustl.edu
Program affiliation
Neurosciences
Research summary
Investigating the effects of prematurity and other modifiable clinical and environmental risk factors on neurodevelopmental outcomes in high-risk pediatric populations
Key words
Neurodevelopment; neonate; prematurity; psychopathology; brain injury; MRI; structural connectivity; functional connectivity
Lawrence Snyder, MD, PhD
Professor
- Email: larry@eye-hand.wustl.edu
Program affiliation
Neurosciences
Research summary
Information processing in the cerebral cortex
Key words
behavior, cognition, computational biology, eye-hand coordination, neurophysiology, systems neuroscience
Lilianna Solnica-Krezel, PhD
Professor and Head of the Department of Developmental Biology
- Email: solnical@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Research summary
Inductive and morphogenetic processes that establish and shape germ layers during vertebrate embryogenesis, using zebrafish and embryonic stem cell models
Key words
Gastrulation, Vertebrate embryogenesis, Patterning, Cell movement, Cell signaling, Morphogenesis, Stem Cells
Sheng-Kwei Song, PhD
Professor
- Email: ssong@wustl.edu
Program affiliation
Neurosciences
Research summary
Imaging CNS function and pathology
Key words
diffusion, imaging, multiple sclerosis, retinal degeneration, spinal cord, White matter injury
Andrea Soranno, PhD
Associate Professor
- Email: soranno@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Role of disordered proteins in function and dysfunction: from Alzheimer’s disease to SARS CoV 2
Key words
disordered proteins, single molecule, fluorescence, FRET, Alzheimer’s disease, SARS CoV 2 nucleocapsid, Apolipoprotein E, ApoE, biomolecular condensates, polymer models
George Souroullas, PhD
Assistant Professor
- Email: george.souroullas@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Understand how epigenetic mechanisms and chromatin dynamics contribute towards the development of cancer.
Key words
Epigenetics, chromatin, cancer, mouse models, lymphoma, melanoma, EZH2, PRC2, H3K27me3
David Spencer, MD, PhD
Associate Professor
- Email: dspencer@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Computational and Systems Biology
Research summary
My research program studies DNA methylation in cancer, with a specific emphasis on understanding the origin, evolution, and functional impact of cancer-associated DNA methylation changes and how these can be used as biomarkers of clinical outcomes.
Key words
epigenetics, methylation, gene regulation, cancer, leukemia, genomics