Faculty

DBBS mentors and educators are key to our training mission. Those who serve as primary mentors are DBBS Program Members, and others who participate in the educational mission are General Members. Learn about DBBS Faculty Membership »

To provide a supportive learning environment for our trainees, many DBBS-affiliated faculty have completed eight or more hours of CIMER-based mentorship training with a trained facilitator, as indicated below with a profile badge.

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Find faculty of interest by entering a name, program or expertise keyword in the search bar; selecting a PhD program from the drop-down menu; or selecting the last name initial from the A-Z filter.

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Philip Stahl, PhD

Edward Mallinckrodt Jr Professor Emeritus

Program affiliation
General

Research summary
Exosomes- biogenesis and secretion. Hominoid-specific genes such as TBC1D3, that regulate growth factor receptor signaling, may help explain human evolution and physiology

Key words
Exosomes, endocytosis, hominoid-specific genes

Christina Stallings, PhD

Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology

Research summary
Molecular pathogenesis of Mycobacterium tuberculosis

Key words
bacteria, gene regulation, molecular genetics, microbiology, pathogenesis, transcription, infectious disease, innate immunity

Ashley Steed, MD, PhD

Assistant Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
Investigate the genetic and environmental factors that underlie the mechanistic basis for the heterogeneity in outcomes in response to infection

Key words

Alexander Stegh, PhD

Professor

Program affiliation
Cancer Biology

Research summary
Glioblastoma metabolism, mechanisms of immunosupression, and the development of novel gene-regulatory and immunostimulatory nanotechnologies

Key words

Paul Stein, PhD

Professor

Program affiliation
Neurosciences

Research summary
Sensorimotor integration; spinal cord neural networks; turtle hindlimb motor output

Key words
behavior, central pattern generators, neurobiology, physiology, spinal cord

William Stenson, MD

Professor Emeritus of Medicine

Program affiliation
General

Research summary
We are interested in the epithelial response to injury in the intestine and in mucosal immununology in the intestine.

Key words
apoptosis, epithelial cells, immunology, inflammation, innate immunity, prostaglandin, radiation

Sheila Stewart, PhD

Professor

Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology

Research summary
Examining the role the tumor microenvironment plays in immune modulation, tumor development, metastasis and dormancy

Key words
aging, cancer, microenvironment, RNAi, senescence, telomere

Nathan Stitziel, MD, PhD

Professor

Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Computational and Systems Biology
Biomedical Informatics and Data Science

Research summary
We use multiomic approaches to discover mechanisms underlying cardiovascular disease and leverage these insights to identify new drug targets.

Key words
Human genetics; cardiovascular disease

Stephen Stone, MD

Assistant Professor

Program affiliation
Developmental Regenerative and Stem Cell Biology

Research summary
Work in our lab focuses on the role of insulin resistance in human metabolic diseases. To accomplish this, we focus our efforts on patients with severe insulin resistance syndromes.

Key words
Insulin Resistance, Atypical Diabetes, Pediatric Endocrinology, FGF21, Fibroblast Growth factors

Gary Stormo, PhD

Joseph Erlanger Professor Emeritus of Genetics

Program affiliation
General

Research summary
Computational biology, bioinformatics, protein-DNA interactions, gene regulation

Key words
computational biology, genome analysis, gene expression, mathematical modeling

Jennifer Strahle, MD

Associate Professor

Program affiliation
Neurosciences

Research summary
To understand and develop treatments for cerebrospinal fluid circulation disorders during development, including neonatal post-hemorrhagic hydrocephalus

Key words

Joan Strassmann, PhD

Charles Rebstock Professor

Program affiliation
Ecology and Evolutionary Biology
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences

Research summary
We work on social interactions and mutualism using a microbial system so we can study cheating, conflict and cooperation at experimental and genomic levels, within and between species, in particular in social amoebae and their farmed bacteria

Key words
social evolution; multicellularity; mutualism; symbiosis; experimental evolution; disease; social amoebae; Dictyostelium; science education; birds

Amber Stratman, PhD

Associate Professor

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology

Research summary
The Stratman lab is broadly interested in how blood vessels form and stabilize during development, and how changes in these processes affect tissue homeostasis and disease.

Key words
mechanobiology, vascular, endothelial cell, blood flow

Eva-Maria Strauch, PhD

Associate Professor

Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Biomedical Informatics and Data Science
Molecular Genetics and Genomics

Research summary

Key words
protein design, protein engineering, influenza, RSV, machine learning , vaccines, antivirals

Yidan Sun, PhD

Assistant Professor

Program affiliation
General

Research summary

Key words

Siobhan Sutcliffe, PhD, ScM, MHS

Associate Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biomedical Informatics and Data Science

Research summary
Infectious causes of cancer and chronic diseases

Key words

Joshua Swamidass, MD, PhD

Associate Professor

Program affiliation
Computational and Systems Biology
Biomedical Informatics and Data Science

Research summary
We computationally model drug metabolism to predict drug toxicity and to assist pathologists in assessing histology images.

Key words
deep learning, metabolism, pathology, image analysis, machine learning, bioinformatics, biostatistics, chemical informatics, drug and target discovery, drug design

Stephen Sykes, PhD

Associate Professor

Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Identify and define those molecular features that drive leukemogenesis and then use that information to develop rational therapeutic strategies for improving outcomes in acute leukemia

Key words
leukemia, metabolism, therapy resistance, stem cells

Chad Sylvester, MD, PhD

Associate Professor

Program affiliation
Neurosciences

Research summary
Characterizing functional brain network development in children with and without anxiety disorders, with the long-term goal of using this information to devise novel, mechanism-based treatments for pediatric anxiety disorders.

Key words

Aydan Szeto, PhD

Assistant Professor

Program affiliation
Immunology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
We investigate how the immune system maintains balance during healthy homeostasis, and when this balance is thrown off, how the dysregulated activities of the same immune cells cause immune diseases such as asthma, allergy and autoimmunity. We focus on type 2 lymphocytes, namely ILC2s and Th2 cells, and apply high-throughput CRISPR screens to identify novel regulators of type 2 immune responses. We are a multidisciplinary laboratory combining molecular, in vitro and in vivo approaches to understand the underlying mechanisms of immune cell function in homeostasis and allergic diseases. By advancing our basic understanding of how immune cells develop and function, we aim to develop novel approaches to restoring immune balance and promoting tissue and organismal health.

Key words
type 2 immunity, innate lymphoid cells, ILC2, Th2, allergy, asthma, CRISPR screen, computational, transcriptomic, epigenetic, tissue immunity, mucosal immunity, neuroimmune

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